Within the framework of the European Union Chemical Biological Radiological and Nuclear Centres of Excellence (EU CBRN CoE) Initiative, a regional Action Plan Workshop for the Middle East was organized by the Regional CBRN CoE Secretariat with the support of UNICRI from 09-11 July 2024 in Amman, Jordan. The event, aimed to discuss the Regional Action Plan (RAP) to develop a comprehensive framework to address the multifaceted challenges posed by chemical, biological, radiological, and nuclear threats in the region.